Hypospadias is a common congenital urological anomaly with a ventrally located urethral meatus with a prevalence of 5–50 per 10,000 births. Trial registration number The trial is registered at with trial registration number: NCT04876976 (retrospective registration) However, we could not demonstrate a statistically significant difference between the two groups. The successful repair of UCF was found to be higher with cyanoacrylate. The application of cyanoacrylate during UCF repair was feasible and safe. There was no statistically significant difference between both groups as regards the occurrence of mild complications in the postoperative period, which was 10% in both groups. Successful UCF closure was achieved in 80% of cases in group I (16/20) and 70% of group II (14/20) with no statistically significant difference. The mean fistula size was 3.25 ± 0.64 and 3.15 ± 0.75 mm in group I and II, respectively, with a statistically significant difference. There was no statistically significant difference between the two groups regarding their demographic data. Resultsįorty patients were available for evaluation at the end of our study. We followed up our patients for 6 months following the procedure to evaluate a successful closure. Group I represented a multilayered closure with dartos fascia flap while using cyanoacrylate glue as an interposition layer, while group II represented the same procedure without applying the glue. Methodsīetween January 2017 and July 2018, 40 patients with UCF were randomized into two equal groups. We aim to evaluate isoamyl 2-cyanoacrylate as an intervening layer in the surgical repair of the urethra-cutaneous fistula (UCF) after hypospadias in comparison with the classic surgical repair technique.
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